Your skin’s collagen production begins to decline in your mid to late twenties. You may not immediately notice, but over time, you will see a reduction in firmness, increased fine lines, and less bounce when you gently pinch your face. This process accelerates when your skin is exposed to ultraviolet light, pollution, stress, poor sleep, and an unhealthy diet.
The good news is that you can support your collagen levels with effective, clean, science-backed skincare. There is no need for needles or downtime. With consistent use of the right ingredients, you can protect and improve your skin’s structure.
In this article, you will discover how Trylagen and Pseudoalteromonas ferment extract work together in CallistaÉVA’s Advanced Collagen Serum to create firmer, more hydrated, and radiant skin naturally and elegantly.
Why Collagen Support Matters after Age Twenty-Five
The protein that is most common in your skin is collagen. It forms fibers that give the dermis structure, elasticity, and resilience. When you are young, your body replaces collagen quickly and efficiently. By your mid-20s, that process starts to slow. Over the years, your skin produces less collagen, and the fibers that are present break down more easily. Over time, signs such as fine lines, sagging, and dullness begin to appear.
When collagen breaks down, your skin may become more fragile and develop deeper lines. Layers of moisture evaporate more easily, and the skin barrier weakens. As a result your skin can feel rough rather than soft. Part of what makes modern skincare so powerful is the ability to support your skin’s natural renewal early on before major damage sets in.
You do not have to go for intense medical treatments to protect collagen. Injections or lasers may offer quick results, but they can also involve side effects or a recovery period. A science-backed serum can complement professional treatments or serve as a preventative daily solution. For busy professionals and skincare lovers aged twenty five to forty five this approach makes sense. It fits into a modern routine without complex steps or trade-offs. Science and nature can work together to support your skin’s strength and resilience.
What Is Trylagen and How Does It Work
Trylagen is a patented peptide complex explicitly developed for skincare. It combines tripeptide‑1, tripeptide‑10 citrulline, and complementary protein molecules in a structured three‑phase action. This formula is designed to:
- Encourage fibroblasts in the dermis to produce new collagen
- Align and reorganize collagen fibers for skin resilience
- Help reduce breakdown of existing collagen fibers
These steps work together to restore and maintain structural support in the dermis. Numerous cosmetic studies demonstrate that Trylagen promotes firmer skin and helps prevent lines from deepening. Addressing early signs of aging, it provides a way to support skin health before damage becomes visible. That makes it ideal for individuals aged 25 to 45 who may be just starting to notice changes.
What Is Pseudoalteromonas Ferment Extract
Pseudoalteromonas ferment extract is a marine‑derived molecule originally known as Antarcticine. It is a glycoprotein secreted by the bacterium Pseudoalteromonas Antarctica. This microorganism lives in freezing environments near King George Island in Antarctica. To survive the cold, it produces Antarcticine to prevent ice crystals from damaging its cell membranes.
In skincare, this extract offers key benefits:
● Moisture retention, even in challenging environments
● Support of collagen production (Collagen I and Collagen IV) and elastin
● Relief for post-procedure or acutely dry skin
Studies show that at just 5% concentration in formulations, Antarcticine:
● Boosts Collagen I production by 128 percent in skin cells after 15 days
● Raises Collagen IV by 81 percent and elastin by 31 percent over the same period
● Produces a 50 percent reduction in wrinkle depth around the eyes in clinical testing
These results highlight both the collagen and hydration benefits offered by this extract (3). Additionally, the glycoprotein layer helps seal in moisture and protect the skin barrier from environmental stress. This makes it an ideal complement to collagen-supporting peptides.
Combined Action in CallistaÉVA’s Advanced Collagen Serum
Advanced Collagen Serum blends Trylagen and Antarctica ferment extract into a lightweight formulation that absorbs quickly. It is styled for modern skincare routines. No convoluted steps or wait times. Just cleanse, apply the serum, and follow with your choice of moisturizer and sunscreen in the morning.
Why Does This Combination Work
● Trylagen supports long‑term collagen health
● Antarctica extract supplies intense hydration and immediate barrier support
● Together, they promote skin firmness, texture improvement, and a smoother surface
● Ideal for early signs of aging and general skin resilience
Ingredient Profile
● Peptide nutrients for fibroblast stimulation
● Marine glycoprotein for deep hydration
● Free from parabens, sulfates, artificial dyes, and fragrances
● Made for both men and women, all skin tones, and most skin types
Scientific Support for Marine‑Derived Collagen Enhancers
Marine Collagenases And Hydrolysate
A study on collagenase enzymes from Pseudoalteromonas sp SJN2 showed that the bacteria produced collagenases with an outstanding yield (322.58 ± 9.61 U·mL – 1). These enzymes broke down collagen into peptides with antioxidant effects measured by DPPH scavenging and ORAC assays under optimized fermentation conditions (1). The antioxidant peptides can combat free radicals on the skin and support cellular health.
Collagen Oligopeptides From Pseudoalteromonas Sm9913
Another study used a serine collagenolytic protease from Pseudoalteromonas SM9913 to hydrolyze fish collagen into oligopeptides under 3 kDa. The hydrolysate maintained over 95 percent of peptides below 3 kDa and about 60 percent below 1 kDa. Lab and pilot scale trials confirmed the hydrolysate had excellent moisture retention, antioxidant activity, and supported human dermal fibroblast viability without irritation (2). The process scaled up to 100 L and 2000 L with consistent quality.
These two studies mirror how marine microbes like Pseudoalteromonas can generate functional compounds with skin benefits. It confirms that molecules derived from marine fermentation, similar in nature to peptides and Antarctica extract, can support collagen and moisture in skincare ingredients.
Certification and Safety
CallistaÉVA ensures all ingredients meet strict standards. Both Trylagen and Antarctica extracts come from certified suppliers. Products are tested for purity, stability, and safety. Antarctica extract has passed human cell culture tests and topical use studies with no skin irritation. The Advanced Collagen Serum does not contain parabens, phthalates, or artificial fragrance, and is safe for sensitive skin types. Dermatologist feedback affirms its suitability for daily use.
These Benefits Support Busy Lifestyles and Skin Confidence
The Advanced Collagen Serum is designed for those who:
● Have busy routines and limited time for skincare.
● Prefer holistic routines without invasive treatments.
● Appreciate clean, science-backed ingredients.
● Want effective results without aggressive procedures.
Apply it morning and evening after cleansing. A few gentle taps of serum to the face and neck build a resilient base for further care. It layers well under moisturizers and makeup. Use it consistently, and you nourish your skin’s foundation.
Who Should Use the Serum?
Ideal Candidates
● Anyone aged 25 to 45, noticing firmness loss or fine lines.
● All gender identities and skin undertones.
● Those with dry, stressed, or dull skin, especially in dry or air-conditioned environments.
● People wanting powerful results without injections.
● Anyone seeking a simplified yet effective routine.
It is not recommended for people allergic to bacteria-derived ingredients. Always patch test first, especially if you have sensitive or compromised skin.
Why This Is a Modern Alternative to Aggressive Treatments
The serum is designed to support your skin in daily life. Some key benefits compared with medical procedures:
● No needles or downtime.
● Lower risk of side effects.
● Supports your skin’s natural processes rather than invading them.
● Fits into your morning and night routine.
● Results build over time resurfacing texture and tone.
This aligns with time saving skincare that still delivers results for confident and educated skincare lovers.
Tips for Best Results
- Use morning and evening, right after cleansing.
- Pat serum onto face and neck until absorbed.
- Follow with moisturizer, and in the day, add sunscreen SPF 30 or higher.
- Maintain healthy habits: sleep, water, a balanced diet, and exercise.
- Combine with antioxidants like vitamin C to further protect collagen.
- Reapply light moisturizer or serum after exfoliation or sun exposure.
A consistent routine maximizes the serum’s benefits.
Final Thoughts
Supporting collagen does not require invasive or uncomfortable procedures. CallistaÉVA’s Advanced Collagen Serum uses marine and peptide science to strengthen, hydrate and rejuvenate your skin from within. The synergy of Trylagen and Pseudoalteromonas ferment extract offers a powerful approach that fits today’s lifestyle and ethical values. It takes minutes a day yet delivers firm, healthy looking skin over time.
References:
- Yang, Xinghao, et al. "Optimization of collagenase production by Pseudoalteromonas sp. SJN2 and application of collagenases in the preparation of antioxidative hydrolysates." Marine Drugs 15.12 (2017): 377.
https://pubmed.ncbi.nlm.nih.gov/29207560/ - Chen, Xiu-Lan, et al. "Preparation and functional evaluation of collagen oligopeptide-rich hydrolysate from fish skin with the serine collagenolytic protease from Pseudoalteromonas sp. SM9913." Scientific Reports 7.1 (2017): 15716.
https://pubmed.ncbi.nlm.nih.gov/29146927/ - Pseudoalteromonas Ferment Extract
https://inci.guide/marine-extracts/pseudoalteromonas-ferment-extract